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Domestic exclusive, Jiankang Yuan Lishu Tong® is recommended as a first-line drug for childhood asthma
Published Time:
2020-09-14
Recently, the Respiratory Group of the Pediatrics Branch of the Chinese Medical Doctor Association and the Pediatric Physician Branch of the Chinese Medical Doctor Association jointly issued the "Recommendations for the Standardized Diagnosis and Treatment of Childhood Bronchial Asthma (2020 Edition)" (hereinafter referred to as the "Treatment Recommendations"), providing a useful reference for the standardized and homogenized diagnosis and treatment of childhood asthma in China. Among them, levalbuterol, as a newly launched inhalation preparation, is also recommended as the first-line drug of choice for treating acute attacks.
Levalbuterol hydrochloride nebulization inhalation solution, as an inhalation preparation, is a typical complex preparation. This type of product is difficult to imitate, has a low degree of domestic production, and is heavily reliant on imports. It is an inhalation preparation that the country prioritizes and encourages research and development. In 2018, it entered the "29th batch of drug registration applications to be included in the priority review procedure" list as a "major project" and "pediatric drug". It is worth mentioning that Joincare Pharmaceutical Group Industry Co., Ltd. (hereinafter referred to as "Health Yuan"), with its product levalbuterol hydrochloride nebulization inhalation solution (Lishutong®), has become the only domestic listed company producing and supplying first-line drugs for the treatment of childhood asthma!
Currently, clinically used salbutamol is also a first-line reliever drug for children with asthma, which can quickly relieve airway symptoms in patients. However, its dextrorotatory component will enhance bronchoconstriction, leading to tachycardia, hypokalemia, or hyperglycemia in patients. In severe cases, acidosis may occur. The listing of levalbuterol makes up for many shortcomings of existing salbutamol, bringing new choices for Chinese children.
Due to the many advantages of inhalation administration, the market is rapidly rising, and the domestic market for respiratory inhalation preparations has broad prospects. However, due to the high R&D barriers of respiratory inhalation preparations, the vast majority of the Chinese market share has long been occupied by several foreign pharmaceutical companies in Europe, America, and Japan.
Health Yuan is one of the earliest domestic companies to deploy inhalation preparations. It is in a leading position in China in terms of R&D investment and pipeline. As a comprehensive pharmaceutical group company integrating R&D, production, sales, and service, under the innovative keynote of Chairman Zhu Baoguo, the group has always insisted on using respiratory drug delivery technology platforms and other characteristic and innovative R&D technology platforms as breakthroughs, continuously and deeply deploying in the field of inhalation preparations. After years of development, the company has now formed a relatively focused and clear product R&D pipeline.
According to publicly available information, Health Yuan obtained the registration certificate for levalbuterol hydrochloride nebulization inhalation solution (Lishutong®) in September 2019, and the small-specification children's special dosage form was approved in August this year. This time, Lishutong® was included in the "Recommendations for Standardized Diagnosis and Treatment of Childhood Bronchial Asthma" and the "Expert Consensus on the Integrated Traditional Chinese and Western Medicine Prevention and Treatment of Childhood Asthma", which reflects Health Yuan's high attention to the R&D, production, and implementation of respiratory preparations, as well as the recognition of its products and technologies by the country and the pharmaceutical industry.
No matter what industry you are in, improving independent innovation capabilities, mastering core technologies in key areas, and avoiding being "stuck" are crucial to the country's development. Health Yuan has been deeply involved in the pharmaceutical industry, constantly breaking through and daring to innovate. While breaking the foreign monopoly on respiratory preparations and achieving its own dreams, it has also proved to the world the high spirits and strong potential of Chinese pharmaceutical companies.
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